Pub. Date : 2013 Mar 29
PMID : 23485471
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Enhanced expression of p-CREB and PGC-1alpha induced by cilostazol could be inhibited by H-89. | Cilostazol | cAMP responsive element binding protein 1 | Homo sapiens |
| 2 | Moreover, the increased expression of PGC-1alpha induced by cilostazol could be inhibited by downregulation of CREB using CREB siRNA at both mRNA and protein levels. | Cilostazol | cAMP responsive element binding protein 1 | Homo sapiens |
| 3 | Moreover, the increased expression of PGC-1alpha induced by cilostazol could be inhibited by downregulation of CREB using CREB siRNA at both mRNA and protein levels. | Cilostazol | cAMP responsive element binding protein 1 | Homo sapiens |
| 4 | All the results indicated that cilostazol promoted mitochondrial biogenesis through activating the expression of PGC-1alpha in HUVECs, which was mediated by PKA/CREB pathway. | Cilostazol | cAMP responsive element binding protein 1 | Homo sapiens |