Title : The effect of mitotane on viability, steroidogenesis and gene expression in NCI‑H295R adrenocortical cells.

Pub. Date : 2013 Mar

PMID : 23254310






1 Functional Relationships(s)
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1 Concomitantly, mitotane resulted in decreased mRNA levels of two cytochromes P450 (CYP11A1 and CYP17A1), mRNAs encoding proteins involved in the synthesis of cortisol and DHEAS. Hydrocortisone cytochrome P450 family 17 subfamily A member 1 Homo sapiens