Title : Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism.

Pub. Date : 2012

PMID : 23166782






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Sirtuin 3 (SIRT3) is a mitochondrial protein deacetylase that regulates the function of the electron transport chain and maintains basal ATP yield. Adenosine Triphosphate sirtuin 3 Mus musculus
2 Sirtuin 3 (SIRT3) is a mitochondrial protein deacetylase that regulates the function of the electron transport chain and maintains basal ATP yield. Adenosine Triphosphate sirtuin 3 Mus musculus
3 We hypothesized that metformin treatment could diminish mitochondrial ATP production through downregulation of SIRT3 expression. Adenosine Triphosphate sirtuin 3 Mus musculus