Title : Novel role for SHP-2 in nutrient-responsive control of S6 kinase 1 signaling.

Pub. Date : 2013 Jan

PMID : 23129808






1 Functional Relationships(s)
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1 Activation of S6K1 by leucine requires the mobilization of intracellular calcium (Ca(2+)), which we show is mediated by SHP-2 in an inositol-1,4,5-trisphosphate-dependent manner. Calcium protein tyrosine phosphatase non-receptor type 11 Homo sapiens