PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23129808-5 2013 Activation of S6K1 by leucine requires the mobilization of intracellular calcium (Ca(2+)), which we show is mediated by SHP-2 in an inositol-1,4,5-trisphosphate-dependent manner. Calcium 73-80 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 120-125