Pub. Date : 2012 Nov
PMID : 22922961
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Simultaneous exposure of sites in von Willebrand factor for glycoprotein Ib binding and ADAMTS13 cleavage: studies with ristocetin. | Ristocetin | von Willebrand factor | Homo sapiens |
| 2 | Because ristocetin induces VWF to bind glycoprotein Ibalpha in the absence of shear stress, we evaluated whether it could also enhance ADAMTS13 proteolysis of VWF. | Ristocetin | von Willebrand factor | Homo sapiens |
| 3 | Ristocetin accelerated ADAMTS13 cleavage of multimeric VWF and of each of the recombinant VWF fragments except for the A2 domain lacking the ristocetin-binding site. | Ristocetin | von Willebrand factor | Homo sapiens |
| 4 | Ristocetin accelerated ADAMTS13 cleavage of multimeric VWF and of each of the recombinant VWF fragments except for the A2 domain lacking the ristocetin-binding site. | Ristocetin | von Willebrand factor | Homo sapiens |