Title : Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA.

Pub. Date : 2012 Jun 24

PMID : 22729222






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Affected dermal fibroblasts showed enhanced basal and epidermal growth factor (EGF)-stimulated phosphatidylinositol 3,4,5-trisphosphate (PIP(3)) generation and concomitant activation of downstream signaling relative to their unaffected counterparts. pip(3) epidermal growth factor Homo sapiens
2 Affected dermal fibroblasts showed enhanced basal and epidermal growth factor (EGF)-stimulated phosphatidylinositol 3,4,5-trisphosphate (PIP(3)) generation and concomitant activation of downstream signaling relative to their unaffected counterparts. pip(3) epidermal growth factor Homo sapiens