Title : Oxidative Stress-Mediated Brain Dehydroepiandrosterone (DHEA) Formation in Alzheimer's Disease Diagnosis.

Pub. Date : 2011

PMID : 22654823






1 Functional Relationships(s)
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1 Over the years we have reported that, unlike other neurosteroids, DHEA biosynthesis in rat, bovine, and human brain is mediated by an oxidative stress-mediated mechanism, independent of the cytochrome P450 17alpha-hydroxylase/17,20-lyase (CYP17A1) enzyme activity found in the periphery. Dehydroepiandrosterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens