PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22654823-4 2011 Over the years we have reported that, unlike other neurosteroids, DHEA biosynthesis in rat, bovine, and human brain is mediated by an oxidative stress-mediated mechanism, independent of the cytochrome P450 17alpha-hydroxylase/17,20-lyase (CYP17A1) enzyme activity found in the periphery. Dehydroepiandrosterone 66-70 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 239-246