Title : The α4β2 nicotine acetylcholine receptor agonist ispronicline induces c-Fos expression in selective regions of the rat forebrain.

Pub. Date : 2012 Apr 25

PMID : 22414858






1 Functional Relationships(s)
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1 The restricted distribution of c-Fos to these areas, all of which are directly or indirectly involved in acute stress regulation after a single dose of ispronicline, supports earlier studies that the alpha4beta2 receptors are strongly involved in nicotine-dependent activation of the hypothalamo-pituitary adrenocortical axis. Nicotine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus