Pub. Date : 1990 Nov
PMID : 2233710
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this report, we demonstrate that the PEER T-cell line (bearing gamma/delta T-cell receptors) accumulates CSP-B mRNA following exposure to 12-O-tetradecanoylphorbol-13-acetate (TPA) and N6-2"-O-dibutyryladenosine 3",5"-cyclic monophosphate (bt2cAMP) because of transcriptional activation of the CSP-B gene. | Tetradecanoylphorbol Acetate | granzyme B | Homo sapiens |
| 2 | In this report, we demonstrate that the PEER T-cell line (bearing gamma/delta T-cell receptors) accumulates CSP-B mRNA following exposure to 12-O-tetradecanoylphorbol-13-acetate (TPA) and N6-2"-O-dibutyryladenosine 3",5"-cyclic monophosphate (bt2cAMP) because of transcriptional activation of the CSP-B gene. | Tetradecanoylphorbol Acetate | granzyme B | Homo sapiens |
| 3 | TPA and bt2cAMP act synergistically to induce CSP-B expression, since neither agent alone causes activation of CSP-B transcription or mRNA accumulation. | Tetradecanoylphorbol Acetate | granzyme B | Homo sapiens |
| 4 | TPA and bt2cAMP act synergistically to induce CSP-B expression, since neither agent alone causes activation of CSP-B transcription or mRNA accumulation. | Tetradecanoylphorbol Acetate | granzyme B | Homo sapiens |
| 5 | Chromatin upstream from the CSP-B gene is resistant to DNase I digestion in untreated PEER cells, but becomes sensitive following TPA-bt2cAMP treatment. | Tetradecanoylphorbol Acetate | granzyme B | Homo sapiens |