PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2233710-2 1990 In this report, we demonstrate that the PEER T-cell line (bearing gamma/delta T-cell receptors) accumulates CSP-B mRNA following exposure to 12-O-tetradecanoylphorbol-13-acetate (TPA) and N6-2"-O-dibutyryladenosine 3",5"-cyclic monophosphate (bt2cAMP) because of transcriptional activation of the CSP-B gene. Tetradecanoylphorbol Acetate 141-177 granzyme B Homo sapiens 108-113 2233710-2 1990 In this report, we demonstrate that the PEER T-cell line (bearing gamma/delta T-cell receptors) accumulates CSP-B mRNA following exposure to 12-O-tetradecanoylphorbol-13-acetate (TPA) and N6-2"-O-dibutyryladenosine 3",5"-cyclic monophosphate (bt2cAMP) because of transcriptional activation of the CSP-B gene. Tetradecanoylphorbol Acetate 179-182 granzyme B Homo sapiens 108-113 2233710-3 1990 TPA and bt2cAMP act synergistically to induce CSP-B expression, since neither agent alone causes activation of CSP-B transcription or mRNA accumulation. Tetradecanoylphorbol Acetate 0-3 granzyme B Homo sapiens 46-51 2233710-3 1990 TPA and bt2cAMP act synergistically to induce CSP-B expression, since neither agent alone causes activation of CSP-B transcription or mRNA accumulation. Tetradecanoylphorbol Acetate 0-3 granzyme B Homo sapiens 111-116 2233710-4 1990 Chromatin upstream from the CSP-B gene is resistant to DNase I digestion in untreated PEER cells, but becomes sensitive following TPA-bt2cAMP treatment. Tetradecanoylphorbol Acetate 130-133 granzyme B Homo sapiens 28-33