Title : GABA, glutamate, dopamine and serotonin transporters expression on memory formation and amnesia.

Pub. Date : 2012 Feb

PMID : 22183017






3 Functional Relationships(s)
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1 Hence, in this paper Western-blot analysis was used to evaluate expression changes on them during memory formation in trained and untrained rats treated with the selective serotonin transporter inhibitor fluoxetine, the amnesic drug d-methamphetamine (METH) and fluoxetine plus METH. Methamphetamine solute carrier family 6 member 4 Rattus norvegicus
2 The METH-induced amnesia down-regulated SERT, DAT, EACC1 and GAT1 in hippocampus and the GAT1 in striatum; no-changes were observed in prefrontal cortex. Methamphetamine solute carrier family 6 member 4 Rattus norvegicus
3 Fluoxetine plus METH administration was able to prevent amnesia, which was associated to DAT, EACC1 and GAT1 (prefrontal cortex), SERT and DAT (hippocampus) and EACC1 or DAT (striatal) up-regulation. Methamphetamine solute carrier family 6 member 4 Rattus norvegicus