Title : Clinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer.

Pub. Date : 2012 Feb

PMID : 22170708






1 Functional Relationships(s)
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1 RESULTS: Treatment with single-agent abiraterone acetate was associated with accumulation of steroids with mineralocorticoid properties upstream of CYP17A1. Steroids cytochrome P450 family 17 subfamily A member 1 Homo sapiens