Title : Activation of the HIF prolyl hydroxylase by the iron chaperones PCBP1 and PCBP2.

Pub. Date : 2011 Nov 2

PMID : 22055506






10 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Activation of the HIF prolyl hydroxylase by the iron chaperones PCBP1 and PCBP2. Iron poly(rC) binding protein 1 Homo sapiens
2 Human poly (rC) binding protein 1 (PCBP1) is an iron chaperone that binds iron and delivers it to ferritin, a cytosolic iron storage protein. Iron poly(rC) binding protein 1 Homo sapiens
3 Human poly (rC) binding protein 1 (PCBP1) is an iron chaperone that binds iron and delivers it to ferritin, a cytosolic iron storage protein. Iron poly(rC) binding protein 1 Homo sapiens
4 Human poly (rC) binding protein 1 (PCBP1) is an iron chaperone that binds iron and delivers it to ferritin, a cytosolic iron storage protein. Iron poly(rC) binding protein 1 Homo sapiens
5 We have identified the iron-dependent prolyl hydroxylases (PHDs) and asparaginyl hydroxylase (FIH1) that modify hypoxia-inducible factor alpha (HIFalpha) as targets of PCBP1. Iron poly(rC) binding protein 1 Homo sapiens
6 These data indicated that PCBP1 was required for iron incorporation into PHD and suggest a broad role for PCBP1 and 2 in delivering iron to cytosolic nonheme iron enzymes. Iron poly(rC) binding protein 1 Homo sapiens
7 These data indicated that PCBP1 was required for iron incorporation into PHD and suggest a broad role for PCBP1 and 2 in delivering iron to cytosolic nonheme iron enzymes. Iron poly(rC) binding protein 1 Homo sapiens
8 These data indicated that PCBP1 was required for iron incorporation into PHD and suggest a broad role for PCBP1 and 2 in delivering iron to cytosolic nonheme iron enzymes. Iron poly(rC) binding protein 1 Homo sapiens
9 These data indicated that PCBP1 was required for iron incorporation into PHD and suggest a broad role for PCBP1 and 2 in delivering iron to cytosolic nonheme iron enzymes. Iron poly(rC) binding protein 1 Homo sapiens
10 These data indicated that PCBP1 was required for iron incorporation into PHD and suggest a broad role for PCBP1 and 2 in delivering iron to cytosolic nonheme iron enzymes. Iron poly(rC) binding protein 1 Homo sapiens