Title : p21(WAF1/Cip1/Sdi1) knockout mice respond to doxorubicin with reduced cardiotoxicity.

Pub. Date : 2011 Nov 15

PMID : 21920376






2 Functional Relationships(s)
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1 Measurements of 6 circulating cytokines indicated elevation of IL-6, IL-12, IFNgamma and TNFalpha in Dox treated WT mice but not p21KO mice. Doxorubicin interleukin 6 Mus musculus
2 Dox induced elevation of IL-6 mRNA was detected in the myocardium of WT mice but not p21KO mice. Doxorubicin interleukin 6 Mus musculus