Title : Aquatic birnavirus-induced ER stress-mediated death signaling contribute to downregulation of Bcl-2 family proteins in salmon embryo cells.

Pub. Date : 2011

PMID : 21901118






4 Functional Relationships(s)
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1 Furthermore, with GRP78 synthesis inhibitor momitoxin (VT) and PKR inhibitor 2-aminopurine (2-AP) treatment for blocking GRP78 expression and eIF2alpha phosphorylation, PKR/PERK may involve in eIF2alpha phosphorylation/CHOP upregulation pathway that enhances the downstream regulators Bcl-2 family proteins expression and increased cell survival. 2-Aminopurine eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens
2 Furthermore, with GRP78 synthesis inhibitor momitoxin (VT) and PKR inhibitor 2-aminopurine (2-AP) treatment for blocking GRP78 expression and eIF2alpha phosphorylation, PKR/PERK may involve in eIF2alpha phosphorylation/CHOP upregulation pathway that enhances the downstream regulators Bcl-2 family proteins expression and increased cell survival. 2-Aminopurine eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens
3 Furthermore, with GRP78 synthesis inhibitor momitoxin (VT) and PKR inhibitor 2-aminopurine (2-AP) treatment for blocking GRP78 expression and eIF2alpha phosphorylation, PKR/PERK may involve in eIF2alpha phosphorylation/CHOP upregulation pathway that enhances the downstream regulators Bcl-2 family proteins expression and increased cell survival. 2-Aminopurine eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens
4 Furthermore, with GRP78 synthesis inhibitor momitoxin (VT) and PKR inhibitor 2-aminopurine (2-AP) treatment for blocking GRP78 expression and eIF2alpha phosphorylation, PKR/PERK may involve in eIF2alpha phosphorylation/CHOP upregulation pathway that enhances the downstream regulators Bcl-2 family proteins expression and increased cell survival. 2-Aminopurine eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens