Pub. Date : 2011 Nov 1
PMID : 21784061
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mcl-1 downregulation by YM155 contributes to its synergistic anti-tumor activities with ABT-263. | 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
| 2 | Finally, our data demonstrate that downregulation of Mcl-1 by YM155 synergistically lowers the threshold of Bcl-2 family member inhibitor ABT-263-induced cell death. | 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |