Pub. Date : 2011 Sep 16
PMID : 21775425
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Uncoupling protein 3 (UCP3) modulates the activity of Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) by decreasing mitochondrial ATP production. | Adenosine Triphosphate | uncoupling protein 3 | Homo sapiens |
| 2 | Uncoupling protein 3 (UCP3) modulates the activity of Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) by decreasing mitochondrial ATP production. | Adenosine Triphosphate | uncoupling protein 3 | Homo sapiens |
| 3 | In intact cells, however, UCP3 depletion increased mitochondrial ATP production and strongly reduced the cytosolic and mitochondrial Ca(2+) elevations evoked by histamine. | Adenosine Triphosphate | uncoupling protein 3 | Homo sapiens |
| 4 | Our results indicate that UCP3 is not a mitochondrial Ca(2+) uniporter and that it instead negatively modulates the activity of SERCA by limiting mitochondrial ATP production. | Adenosine Triphosphate | uncoupling protein 3 | Homo sapiens |