PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21775425-0 2011 Uncoupling protein 3 (UCP3) modulates the activity of Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) by decreasing mitochondrial ATP production. Adenosine Triphosphate 87-90 uncoupling protein 3 Homo sapiens 0-20 21775425-0 2011 Uncoupling protein 3 (UCP3) modulates the activity of Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) by decreasing mitochondrial ATP production. Adenosine Triphosphate 87-90 uncoupling protein 3 Homo sapiens 22-26 21775425-4 2011 In intact cells, however, UCP3 depletion increased mitochondrial ATP production and strongly reduced the cytosolic and mitochondrial Ca(2+) elevations evoked by histamine. Adenosine Triphosphate 65-68 uncoupling protein 3 Homo sapiens 26-30 21775425-8 2011 Our results indicate that UCP3 is not a mitochondrial Ca(2+) uniporter and that it instead negatively modulates the activity of SERCA by limiting mitochondrial ATP production. Adenosine Triphosphate 160-163 uncoupling protein 3 Homo sapiens 26-30