Pub. Date : 2011
PMID : 21709421
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Fatty acids and hypoxia stimulate the expression and secretion of the adipokine ANGPTL4 (angiopoietin-like protein 4/ fasting-induced adipose factor) by human adipocytes. | Fatty Acids | angiopoietin like 4 | Homo sapiens |
| 2 | ANGPTL4 (angiopoietin-like protein 4/fasting-induced adipose factor), which is implicated in angiogenesis, lipid metabolism and glucose homeostasis, is a major hypoxia-sensitive gene; recent studies indicate that ANGPTL4 expression is also regulated by fatty acids. | Fatty Acids | angiopoietin like 4 | Homo sapiens |
| 3 | ANGPTL4 (angiopoietin-like protein 4/fasting-induced adipose factor), which is implicated in angiogenesis, lipid metabolism and glucose homeostasis, is a major hypoxia-sensitive gene; recent studies indicate that ANGPTL4 expression is also regulated by fatty acids. | Fatty Acids | angiopoietin like 4 | Homo sapiens |
| 4 | We have examined the effects of hypoxia and fatty acids, alone and together, on the expression and release of ANGPTL4 by human adipocytes. | Fatty Acids | angiopoietin like 4 | Homo sapiens |
| 5 | CONCLUSION: The expression and secretion of ANGPTL4 by human adipocytes is upregulated by both hypoxia and fatty acids. | Fatty Acids | angiopoietin like 4 | Homo sapiens |
| 6 | The stimulatory effect of fatty acids on ANGPTL4 production is augmented under hypoxic conditions. | Fatty Acids | angiopoietin like 4 | Homo sapiens |