Pub. Date : 2011 Sep 30
PMID : 21664904
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Pretreatment with levosimendan reversed the effects of ischaemia and ischaemia/reperfusion on cell viability and enhanced phosphorylation of Akt, p38-mitogen activated protein kinase (MAPK) and extracellular signal-regulated kinases 1/2 (ERK1/2). | Simendan | mitogen-activated protein kinase 1 | Homo sapiens |
2 | Levosimendan stimulated the phosphorylation of Akt, ERK1/2 and p38-MAPK with different kinetics and the activation of these pathways was dependent on the opening of the mitochondrial K(ATP) channels and the production of oxygen free radicals. | Simendan | mitogen-activated protein kinase 1 | Homo sapiens |