Title : Conformational conversion of PDE5 by incubation with sildenafil or metal ion is accompanied by stimulation of allosteric cGMP binding.

Pub. Date : 2011 Oct

PMID : 21620965






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 After incubation with EDTA, addition of Mn(++) or Mg(++) caused reversion of Band 1 to a Band 2/Band 3 PDE5 mixture in which Band 3 PDE5 predominated. Magnesium phosphodiesterase 5A Homo sapiens
2 After incubation with EDTA, addition of Mn(++) or Mg(++) caused reversion of Band 1 to a Band 2/Band 3 PDE5 mixture in which Band 3 PDE5 predominated. Magnesium phosphodiesterase 5A Homo sapiens