Title : Role for PPARĪ³ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts.

Pub. Date : 2011 Aug

PMID : 21507897






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In precision-cut liver slices (PCLSs) and hepatocytes, rosiglitazone either alone or in combination with oleic acid increased triglyceride accumulation, an effect that was blocked by the PPARgamma antagonist biphenol A diglycidyl ether (BADGE). Oleic Acid peroxisome proliferator activated receptor gamma Mus musculus
2 PCLSs and hepatocytes from PPARgamma(Deltahep) mice showed blunted responses to rosiglitazone and oleic acid, whereas the response to these compounds remained intact in PCLSs from PPARgamma(Deltamac) mice. Oleic Acid peroxisome proliferator activated receptor gamma Mus musculus