Pub. Date : 2011 Mar
PMID : 21390270
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Indeed, S(GDP) of Galpha(t), is characterized by a more extensive energy coupling between nucleotide binding site and distal regions involved in GEF recognition compared to small G proteins, which attenuates in the active state. | Guanosine Diphosphate | succinate-CoA ligase GDP/ADP-forming subunit alpha | Homo sapiens |
| 2 | Collectively, nucleotide binding changes the information flow through the conserved Ras-like domain, where GDP enhances the flexibility of mechanically distinct portions involved in nucleotide switch, and favors long distance allosteric communication (in Galpha proteins), compared to GTP. | Guanosine Diphosphate | succinate-CoA ligase GDP/ADP-forming subunit alpha | Homo sapiens |