Protein Name succinate-CoA ligase GDP/ADP-forming subunit alpha
Organism Homo sapiens
Gene ID 8802
Gene Symbol


UniProt P53597 (SUCA_HUMAN)
Relationships Total Number of functionally related compound(s) : 252
Total Number of Articles : 394

succinate-CoA ligase GDP/ADP-forming subunit alpha

Gene Summary

This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq, Feb 2010]

  • succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
  • SCS-alpha
  • mitochondrial succinate--CoA ligase [ADP/GDP-forming] subunit alpha
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