Title : Both type I and II IFN induce insulin resistance by inducing different isoforms of SOCS expression in 3T3-L1 adipocytes.

Pub. Date : 2011 Jun

PMID : 21386060






1 Functional Relationships(s)
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1 In addition, adenovirus-mediated overexpression of either SOCS1 or SOCS3 inhibited insulin-induced tyrosine phosphorylation of IRS-1, whereas the reduction of IRS-1 protein was observed only in SOCS3-expressed cells. Tyrosine suppressor of cytokine signaling 1 Homo sapiens