Title : Synthesis and studies on three-compartment flavone-containing combi-molecules designed to target EGFR, DNA, and MEK.

Pub. Date : 2011 May

PMID : 21294849






1 Functional Relationships(s)
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1 In order to induce a tandem targeting of EGFR, DNA, and MEK, we built complex combi-molecules containing an EGFR targeting quinazoline and an aminoethyltriazene moiety linking the entire molecule to PD98059. Quinazolines epidermal growth factor receptor Homo sapiens