Title : S100P is a novel interaction partner and regulator of IQGAP1.

Pub. Date : 2011 Mar 4

PMID : 21177863






3 Functional Relationships(s)
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1 Specifically, the EGF-induced tyrosine phosphorylation of IQGAP1 that is thought to function in assembling signaling intermediates at IQGAP1 scaffolds in the subplasmalemmal region is markedly reduced in cells overexpressing S100P but not in cells expressing an S100P mutant deficient in IQGAP1 binding. Tyrosine IQ motif containing GTPase activating protein 1 Homo sapiens
2 Specifically, the EGF-induced tyrosine phosphorylation of IQGAP1 that is thought to function in assembling signaling intermediates at IQGAP1 scaffolds in the subplasmalemmal region is markedly reduced in cells overexpressing S100P but not in cells expressing an S100P mutant deficient in IQGAP1 binding. Tyrosine IQ motif containing GTPase activating protein 1 Homo sapiens
3 Specifically, the EGF-induced tyrosine phosphorylation of IQGAP1 that is thought to function in assembling signaling intermediates at IQGAP1 scaffolds in the subplasmalemmal region is markedly reduced in cells overexpressing S100P but not in cells expressing an S100P mutant deficient in IQGAP1 binding. Tyrosine IQ motif containing GTPase activating protein 1 Homo sapiens