| Protein Name | IQ motif containing GTPase activating protein 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8826 |
| Gene Symbol | IQGAP1 |
| UniProt | P46940 (IQGA1_HUMAN), A0A024RC65 (A0A024RC65_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
83
Total Number of Articles : 102 |
Description |
IQ motif containing GTPase activating protein 1 |
| Gene Summary |
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008] |
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