Pub. Date : 2004
PMID : 20945566
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | As a consequence, a pegylated liposomal NP preparation of DOX (PLD) was developed and shown to have a long blood circulation half-life (2-3 days versus 5 min for free DOX) and had a very high accumulation in tumors compared to the normal surrounding tissue. | Doxorubicin | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 2 | As a consequence, a pegylated liposomal NP preparation of DOX (PLD) was developed and shown to have a long blood circulation half-life (2-3 days versus 5 min for free DOX) and had a very high accumulation in tumors compared to the normal surrounding tissue. | Doxorubicin | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 3 | In addition, PLD alone had a superior treatment outcome (in comparison to DOX used at the same concentration in combination with two other chemotherapeutic agents) and showed lower toxicity (5). | Doxorubicin | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |