Title : ADRB2 haplotype is associated with glucose tolerance and insulin sensitivity in obese postmenopausal women.

Pub. Date : 2011 Feb

PMID : 20829805






3 Functional Relationships(s)
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1 We examined the hypothesis that ADRB2 Arg16Gly-Gln27Glu haplotype is associated with body composition, glucose tolerance, and insulin sensitivity in obese, postmenopausal women. Glucose adrenoceptor beta 2 Homo sapiens
2 We found that ADRB2 haplotype was independently associated with % body fat, abdominal fat distribution, VO(2(max)), insulin sensitivity (M/DeltaInsulin), and glucose tolerance (ANOVA, P < 0.05 for all). Glucose adrenoceptor beta 2 Homo sapiens
3 This suggests that ADRB2 haplotypes may mediate insulin action, glucose tolerance, and potentially risk for type 2 diabetes mellitus (T2DM) in obese, postmenopausal women. Glucose adrenoceptor beta 2 Homo sapiens