Title : Contribution of P2X7 receptors to adenosine uptake by cultured mouse astrocytes.

Pub. Date : 2010 Nov 1

PMID : 20645413






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Recently, exogenous NAD(+) was reported to enter astrocytes via the P2X7 receptor (P2X7R)-associated channel/pore. NAD purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus
2 Recently, exogenous NAD(+) was reported to enter astrocytes via the P2X7 receptor (P2X7R)-associated channel/pore. NAD purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus
3 Taken together, these results indicate that exogenous NAD(+) is degraded by ectonucleotidases and that adenosine, as its metabolite, is taken up into astrocytes via the P2X7R-associated channel/pore. NAD purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus