Pub. Date : 2010 Jun 24
PMID : 20491440
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Similar to the parent system 4a, the series of largazole depsipeptides 4b-d, but not 2,4"-bithiazole 5a, showed a marked inhibition of recombinant HDAC1 and selectivity over HDAC4, as well as strong pro-apoptotic effects on the NB4 leukemia cell line, but they failed to induce differentiation to mature granulocytes. | largazole | histone deacetylase 4 | Homo sapiens |