PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20491440-2	2010	Similar to the parent system 4a, the series of largazole depsipeptides 4b-d, but not 2,4"-bithiazole 5a, showed a marked inhibition of recombinant HDAC1 and selectivity over HDAC4, as well as strong pro-apoptotic effects on the NB4 leukemia cell line, but they failed to induce differentiation to mature granulocytes.	largazole	47-56	histone deacetylase 4	Homo sapiens	174-179