Title : Adenovirus infection results in alterations of insulin signaling and glucose homeostasis.

Pub. Date : 2010 Jun

PMID : 20388825

1 Functional Relationships(s)
Compound Name
Protein Name
1 Ad vector infection significantly reduced total levels of the insulin receptor (IR), and insulin receptor substrates 1 and 2 (IRS-1, IRS-2) in the liver of rats, resulting in decreased insulin-induced tyrosine phosphorylation of IR, IRS-1, and IRS-2, and decreased interaction of IRS-1 and IRS-2 with phosphoinositide 3-kinase (PI3K). Tyrosine insulin receptor substrate 1 Rattus norvegicus