PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20388825-5 2010 Ad vector infection significantly reduced total levels of the insulin receptor (IR), and insulin receptor substrates 1 and 2 (IRS-1, IRS-2) in the liver of rats, resulting in decreased insulin-induced tyrosine phosphorylation of IR, IRS-1, and IRS-2, and decreased interaction of IRS-1 and IRS-2 with phosphoinositide 3-kinase (PI3K). Tyrosine 201-209 insulin receptor substrate 1 Rattus norvegicus 126-131