Title : Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.

Pub. Date : 2010 Feb

PMID : 20332435






1 Functional Relationships(s)
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1 However, inclusion of curcumin to continued FOLFOX treatment for another 48 h greatly reduced the survival of these cells, accompanied by a concomitant reduction in activation of EGFR, HER-2, IGF-1R and AKT, as well as expression of COX-2 and cyclin-D1. Curcumin epidermal growth factor receptor Homo sapiens