Pub. Date : 2010 Apr 9
PMID : 20230793
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The citrus flavonoids hesperetin and naringenin block the lipolytic actions of TNF-alpha in mouse adipocytes. | naringenin | tumor necrosis factor | Mus musculus |
2 | In this report, we show that hesperetin and naringenin, two citrus flavonoids, inhibit TNF-alpha-stimulated FFA secretion from mouse adipocytes. | naringenin | tumor necrosis factor | Mus musculus |
3 | Moreover, hesperetin and naringenin prevent TNF-alpha from downregulating the transcription of two antilipolytic genes, perilipin and PDE3B. | naringenin | tumor necrosis factor | Mus musculus |
4 | Our results provide novel evidence that hesperetin and naringenin directly inhibit TNF-alpha-stimulated FFA secretion. | naringenin | tumor necrosis factor | Mus musculus |