Pub. Date : 2010 Mar 30
PMID : 20097188
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The extent of brain acetylcholinesterase (AChE) inhibition was reduced due to nicotine co-exposure consistent with an increase in CYP450-mediated dearylation (detoxification) versus desulfuration. | Nicotine | acetylcholinesterase | Rattus norvegicus |
| 2 | The extent of brain acetylcholinesterase (AChE) inhibition was reduced due to nicotine co-exposure consistent with an increase in CYP450-mediated dearylation (detoxification) versus desulfuration. | Nicotine | acetylcholinesterase | Rattus norvegicus |
| 3 | The current study demonstrated that repeated nicotine exposure could alter CPF metabolism in vivo, resulting in altered brain AChE inhibition. | Nicotine | acetylcholinesterase | Rattus norvegicus |