Pub. Date : 2010 May
PMID : 20082303
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Quercetin suppresses HeLa cell viability via AMPK-induced HSP70 and EGFR down-regulation. | Quercetin | epidermal growth factor receptor | Homo sapiens |
| 2 | Furthermore, quercetin sustained epidermal growth factor receptor (EGFR) activation by suppressing the phosphatases, PP2a and SHP-2. | Quercetin | epidermal growth factor receptor | Homo sapiens |
| 3 | Furthermore, quercetin sustained epidermal growth factor receptor (EGFR) activation by suppressing the phosphatases, PP2a and SHP-2. | Quercetin | epidermal growth factor receptor | Homo sapiens |
| 4 | Finally, quercetin increased the interaction between EGFR and Cbl, and also induced the tyrosine phosphorylation of Cbl. | Quercetin | epidermal growth factor receptor | Homo sapiens |
| 5 | Together, these results suggest that quercetin may have anti-tumor effects on HeLa cells via AMPK-induced HSP70 and down-regulation of EGFR. | Quercetin | epidermal growth factor receptor | Homo sapiens |