Pub. Date : 2010 Apr
PMID : 20044803
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In physiological conditions, high intracellular cholesterol levels cause increased synthesis of oxysterols, which activate LXR, thus triggering a transcriptional response for cholesterol secretion and catabolism. | Oxysterols | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |
2 | The inactivation of LXR following PH is related to the reduced oxysterol availability by way of decreased synthesis, and increased sulfation and secretion. | Oxysterols | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |