Title : Pharmacologic inhibitors of IkappaB kinase suppress growth and migration of mammary carcinosarcoma cells in vitro and prevent osteolytic bone metastasis in vivo.

Pub. Date : 2009 Aug

PMID : 19671767






1 Functional Relationships(s)
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1 Celastrol, BMS-345541, and parthenolide abolished IL1beta and tumor necrosis factor alpha-induced IkappaB phosphorylation and prevented nuclear translocation of NF-kappaB and DNA binding. parthenolide tumor necrosis factor Rattus norvegicus