Title : IL-10 suppresses calcium-mediated costimulation of receptor activator NF-kappa B signaling during human osteoclast differentiation by inhibiting TREM-2 expression.

Pub. Date : 2009 Aug 15

PMID : 19625651






1 Functional Relationships(s)
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1 TREM-2-dependent calcium signals are required for RANK-mediated activation of calcium/calmodulin-dependent protein kinase (CaMK)II and downstream MEK and ERK MAPKs that are important for osteoclastogenesis. Calcium mitogen-activated protein kinase 1 Homo sapiens