Title : Atorvastatin reduces the expression of aldo-keto reductases in HUVEC and PTEC. A new approach to influence the polyol pathway.

Pub. Date : 2009 Jun 1

PMID : 19480738






2 Functional Relationships(s)
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1 PURPOSE: Increased flux of glucose via the polyol pathway, oxidative stress and ischaemia lead to the upregulation of the aldose reductase (AR), the key enzyme of the polyol pathway. Glucose aldo-keto reductase family 1 member B Homo sapiens
2 PURPOSE: Increased flux of glucose via the polyol pathway, oxidative stress and ischaemia lead to the upregulation of the aldose reductase (AR), the key enzyme of the polyol pathway. Glucose aldo-keto reductase family 1 member B Homo sapiens