Pub. Date : 2009 Jul
PMID : 19444865
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hyperferritinemia, which suggests that iron overload plays a decisive role in the pathophysiology of insulin resistance and hyperglycemia, is a common finding in both disorders. | Iron | insulin | Homo sapiens |
| 2 | Iron overload will enhance intrahepatic oxidative stress that promotes hepatic fibrosis, interfere with insulin signalling at various levels and may hamper hepatic insulin extraction. | Iron | insulin | Homo sapiens |
| 3 | Furthermore, iron depletion by phlebotomy removes liver iron content and reduces serum glucose and insulin resistance in NAFLD patients. | Iron | insulin | Homo sapiens |
| 4 | Concerning chronic HCV infection, it has been classically assumed that iron overload contributes to insulin resistance associated with virus infection. | Iron | insulin | Homo sapiens |