Title : Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket.

Pub. Date : 2009 Mar

PMID : 19414330






2 Functional Relationships(s)
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1 RESULTS: Three ligand accessible regions (region 1-3) were present in erythromycin-bound CYP3A4, and these dipole moments indicated the same features as ketoconazole- or metyrapone-bound CYP3A4 molecules. Metyrapone cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 RESULTS: Three ligand accessible regions (region 1-3) were present in erythromycin-bound CYP3A4, and these dipole moments indicated the same features as ketoconazole- or metyrapone-bound CYP3A4 molecules. Metyrapone cytochrome P450 family 3 subfamily A member 4 Homo sapiens