Pub. Date : 2007 Aug
PMID : 19356039
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Three neurotransmitters, namely adrenaline, serotonin and tryptamine inhibit the in vitro activity of several cytochrome P450 (CYP) isozymes (CYP1A2, CYP2C9, CYP2D6 and CYP3A). | Epinephrine | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | However, the effect became negligible when adrenaline concentration was decreased to 100 microM: whereas a high inhibitory effect was observed in CYP2D6, CYP2C9 and CYP3A4 enzyme activities, the NADPH reductase activity remains unchanged. | Epinephrine | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |