Title : A new non-natural arginine-like amino acid derivative with a sulfamoyl group in the side-chain.

Pub. Date : 2010 Mar

PMID : 19283444






1 Functional Relationships(s)
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1 The reported results demonstrate that the functionalization of L-ornithine side-chain with a neutral sulfamoyl group can generate an arginine bioisostere which can be used for the synthesis of prototypes of a new class of human thrombin inhibitors. Ornithine coagulation factor II, thrombin Homo sapiens