PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19283444-3 2010 The reported results demonstrate that the functionalization of L-ornithine side-chain with a neutral sulfamoyl group can generate an arginine bioisostere which can be used for the synthesis of prototypes of a new class of human thrombin inhibitors. Ornithine 63-74 coagulation factor II, thrombin Homo sapiens 228-236